14:45 - 14:57

胸腺巨噬細胞透過正調控五碳醣磷酸路徑緩解吞噬凋亡細胞產生的氧化壓力
Thymic-resident macrophages up-regulate pentose phosphate pathway to overcome efferocytosis-induced oxidative stress

蔡宗霖、徐嘉琳
國立陽明交通大學微生物及免疫學研究所
Institute of Microbiology and Immunology, National Yang Ming Chiao Tung University

14:57 - 15:09

NLRP12 參與紅斑性狼瘡正性干擾素標誌
NLRP12 Involves in the Lupus with Positive Interferon Signature

曹彥博、曾方禹、趙之偉、陳明翰、陳斯婷
國立陽明交通大學臨床醫學研究所
Institutes of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan (Republic of China)

15:09 - 15:21

PTEN 協調 BCR 與 TLR9 之訊息傳遞以避免發炎性 B 細胞生成
PTEN coordinates BCR and TLR9 signal to control inflammatory B cell differentiation

蔡佩汝、徐偉展、陳明玉、詹博強、蘇郁文
國家衛生研究院 / 免疫醫學研究中心
Immunology Research Center, National Health Research Institutes, Zhunan Town, Taiwan

15:21 - 15:33

以 P53 依存促凋亡性 lincRNA-p21 長鏈非編碼核醣核酸為標靶利用 CRISPR 基因干擾編輯與短髮夾核糖核酸工具經由抑制細胞凋亡來改善全身性紅斑狼瘡病人與小鼠模型之腎臟炎及肺出血表現
CRISPR Interference and Short Hairpin RNA Targeting P53-Dependent Pro-apoptotic LincRNA-p21 Expression to Improve Lupus Nephritis and Pulmonary Hemorrhage through Reducing Cell Apoptosis in Systemic Lupus Erythematosus Patients and Mouse Models

謝雨彤 ¹、郭品妤 ¹、陳怡成 ^2,3、周祐吉 ⁴、王崇任 ^1,2
1 成功大學醫學院微免所
² 成功大學附設醫院暨醫學院內科部
³ 成功大學醫學院生化所
⁴ 中研院生醫轉譯研究中心
¹Department of Microbiology and Immunology, National Cheng Kung University Medical College,
²Department of Internal Medicine, National Cheng Kung University Hospital and Medical College,
³Departments of Biochemistry and Molecular Biology, National Cheng Kung University Medical College,
⁴Biomedical Translation Research Center, Academia Sinica

15:33 - 15:45

穿膜絲胺酸蛋白酶 hepsin 抑制 STING 介導的第一型干擾素表現
Suppression of STING-mediated type I interferon induction by transmembrane serine protease hepsin

幸芙、徐玉真、蔡淯妃、林淑華、劉旻褘
國立台灣大學醫學院生物化學暨分子生物學研究所
Department of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University

15:45 - 15:57

RNF186 藉由調控潘氏細胞來維持腸道平衡及宿主防禦
E3 Ligase RNF186 Regulates Intestinal Homeostasis and Host Defense by Targeting Paneth Cells

陳郁文、江宏宇、徐志文
中央研究院 生物醫學科學研究所
Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

15:57 - 16:09

利用嵌合自體抗體受體Ｔ細胞清除抗丙型干擾素自體免疫疾病內自體抗體分泌
B Elimination of the anti-interferonautoantibody productizing B cells by reengineering chimeric autoantibody receptor T cells.

彭湛傑、施瀚博、丁靜雅、王浩鵬、顧正崙
長庚大學臨床醫學研究所
上海科技大學生命科學與技術學院
Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan; School of Life Science and Technology, ShanghaiTech University, Shanghai, China

16:09 - 16:21

有效對抗 SARS-CoV-2 變種病毒的抗體雞尾酒療法
Antibody cocktail effective against variants of SARS-CoV-2

姜伯穎
中央研究 院生醫轉譯研究中心
Biomedical Translation Research Center (BioTReC), Academia Sinica