海報論文目錄

1	Immunomodulatory activity of 2-methoxycinnamaldehyde 2-methoxycinnamaldehyde之免疫調節活性程萬里余毓慧程兆明盧布林醫學大學醫學系羅東聖母醫院風濕免疫科
2	Agonistic anti-CD40 monoclonal antibody drives novel metabolic reprograming to trigger M1 macrophages activation 探討anti-CD40 monoclonal antibody調控巨噬細胞抗腫瘤的免疫反應之分子機轉石佩主劉卜慈國家衛生研究院細胞及系統醫學研究所
3	Adenosine 2B receptor promotes IL-10 production by B1a B cells and regulates germinal center-derived autoimmunity in MRL/lpr mice 腺苷受體A2BR促進B1a B細胞產生IL-10並調節生發中心衍生之自體免疫陳明玉¹，蔡佩汝¹，鄭文卉¹，高承源¹，孫光蕙²，蘇郁文^1,* 1國家衛生研究院/免疫醫學研究中心 2國立陽明大學/醫學生物技術暨檢驗學系
4	New CD1d-restricted glycolipids inhibits iNKT-mediated inflammation in mice 新型CD1d專一性醣脂質可抑制iNKT誘發之小鼠免疫反應紀柏羽賴傳穎張麗萍張雅貞中央研究院生物醫學科學研究所
5	To Study the Immunosuppressive Activity of Cyn-1324 in Ovalbumin-sensitized Asthmatic Mice Cyn-1324對於OVA致敏氣喘小鼠的免疫抑制活性之研究郭杰穎¹ , 陳惠民², 郭敏玲^{1, 3} 1長庚大學生物醫學研究所微生物組 2財團法人國家實驗研究院台灣半導體研究中心 3長庚大學醫學院微免科
6	TREM-2-mediated Nitric Oxide Ameliorate UUO-induced Renal Pathologies through Nitration of RORγt 林慶政¹,張笛筠²,吳昀軒¹,黃偉¹, 羅偉綺¹,劉冠甫¹,唐德成^{2, 3}, 陳念榮¹ 1國立陽明大學微生物及免疫學研究所 2國立陽明大學生理學科暨研究所 3臺北榮民總醫院內科部腎臟科
7	Investigation of the effect of Parkinson’s disease-associated leucine-rich repeat kinase 2 on immune response 帕金森氏症相關富白胺酸重複激酶2對於免疫反應影響之探討鄭元剴江皓森國立臺灣大學生命科學系國立臺灣大學基因體與系統生物學學位學程
8	Investigating the effects of Candida tropicalis on experimental colitis 熱帶念珠菌對實驗性結腸炎影響之探討阮提漢(Doan The Ha) 鄭力倢江皓森國立臺灣大學生命科學系國立臺灣大學基因體與系統生物學學位學程
9	Characterization of the mechanisms of anti-GM-CSF monoclonal antibodies isolated from cryptococcosis patients 分析自隱球菌感染病人分離出之GM-CSF單株抗體作用機轉羅郁方王尚煜施瀚博鍾沛翰丁鶴婷丁靜雅顧正崙長庚大學臨床醫學研究所林口長庚醫院外傷急症外科安立璽榮生醫股份有限公司
10	TREM-1 Expressing Tumor associated macrophages (TAMs) Play a Role of Anti-cancer 表現第一型髓細胞觸發受體的腫瘤相關性巨噬細胞具有抗腫瘤的能力李健榕陳念榮陽明大學微生物及免疫學研究所
11	Characteristics the properties of anti-PLA2R antibodies from Membranous nephropathy patients 分析膜性腎炎病人身上分離之anti-PLA2R自體抗體之特性吳采薏, 塗昆樺, 丁鶴婷, 施瀚博, 顧正崙長庚大學林口長庚醫院
12	GILT contributes to the development of autoimmune uveitis in a murine uveitis model induced by active immunizations GILT參與主動免疫所誘導的自體免疫葡萄膜炎發展顏利穎³，洪薇馨³，羅聖旻^1,2，陳怡斌³，沈家瑞^1,2,4* 長庚大學1醫學生物技術暨檢驗學系、2生物醫學研究所、3基隆長庚醫院婦產科、4林口長庚醫院視網膜科
13	Anti-IFN-γ autoantibodies underlie disseminated Talaromyces marneffei infections 瀰漫性馬爾尼菲籃狀菌感染與抗丙型干擾素自體抗體之關係丁靜雅郭靜施瀚博蔡雨寰曹存巍顧正崙長庚大學臨床醫學研究所廣西醫科大學第一附屬醫院皮膚及性病科中國醫學大學臨床醫學研究所陽明大學微生物及免疫所
14	Investigation of the molecular mechanism and signal transduction of GPR97-mediated apoptosis delay of human neutrophils 探討GPR97延緩人類嗜中性白血球凋亡之分子機制及訊號傳遞張育綺林錫賢長庚大學醫學院微生物免疫科
15	Inhaled Exposure to Acrylamide Enhances Allergic Lung Inflammation in a Murine Model 空氣暴露丙烯醯胺會加重小鼠過敏性肺部發炎蘇湘涵¹, 鄭智美², 孫昭玲^{1, 3} 1高雄醫學大學醫學研究所, 2高雄醫學大學生物醫學暨環境生物學系, 3高雄醫學大學環境醫學研究中心
16	Widespread methylome variations of gout 痛風病人的甲基化變異曾家駿,宋婉瑜,林育志,吳正欽,歐燦騰,蔡文展,顏正賢,劉宏文,章順仁高雄醫學大學附設醫院過敏免疫風濕內科高雄大學運動健康休閒學系
17	Schisandrin B exerts antiallergic effects in Th2-mediated allergic asthma via induction of Foxp3+ regulatory T cells by modulating the function of dendritic cells 五味子素B藉由調控樹突狀細胞功能來誘導Foxp3+調節型T細胞之生成以抑制Th2細胞所引起的過敏性氣喘林鉅倫¹, 黃詩珺¹, 李岳倫¹ 1臺北醫學大學醫學系微免學科
18	Heparan Sulfate Is Important for Thymus Growth 硫酸乙酰肝素對於胸腺發育的重要性徐璿博葛一樊國立陽明大學微生物及免疫學研究所
19	Regulation of T-independent B cell response by conventional dendritic cells 傳統樹突細胞對胸腺非依賴性B細胞反應的調控游雅如，李建國國立台灣大學醫學院免疫學研究所
20	Thymic macrophages are derived from embryonic precursors 胸腺巨噬細胞起源於胚胎周庭安¹ 范琇涵¹ 杜岳華² 黃宣誠³ 徐嘉琳¹ 葛一樊¹ 1國立陽明大學微生物及免疫學研究所國立陽明大學生物醫學資訊研究所國立台灣大學生醫電子與資訊學研究所
21	The Presence of Apoptotic Thymocytes Regulates the Expression of Ferroportin (SLC40A1) in Thymic Resident Macrophages 凋亡胸腺細胞的存在調節胸腺常駐巨噬細胞中鐵轉運蛋白（SLC40A1）的表現范琇涵周庭安葛一樊徐嘉琳國立陽明大學微生物及免疫學研究所
22	Dectin-1-NLRP3 inflammasome signaling-dependent mucus secretion guards intestinal epithelium from fungal invasion 小腸上皮藉由Dectin-1-NLRP3發炎體信號分泌黏液以避免真菌感染陳瑋璘劉維仁蔡雨寰國立陽明大學微生物及免疫學研究所
23	Identification and characterization of a novel cellular ligand of GPR97/ADGRG3 in human neutrophils 探討及鑑別獨特表現於人類嗜中性白血球上的GPR97接體朱岱瑩林錫賢長庚大學醫學院微生物免疫科
24	Rosmarinic Acid Attenuates Lipopolysaccharide-induced Acute Lung Injury in a Murine Model 迷迭香酸減緩小鼠模式中酯多醣誘導之急性肺損傷丁乃群¹, 楊賢鴻^2,3, 郭敏玲 ⁴ 1長庚大學臨床醫學研究所 2長庚大學中醫學系 3長庚紀念醫院中醫部 4長庚大學生物醫學所
25	Characterization of anti-interferon-γ autoantibodies from patients with mycobacterial disease in the monoclonal level 自體抗丙型干擾素單株抗體之表徵特性分析施瀚博¹ 丁靜雅¹ 林嘉豪¹ 陳泓愷² 張子文³ 齊治宇⁴ 顧正崙¹ 長庚大學臨床醫學所1 安立璽榮生醫公司2 中央研究院基因體中心3 中國醫學大學成人感染科4
26	Targeting bromodomain and extra terminal domain showed therapeutic potential for systemic sclerosis associated with interstitial lung disease 靶向溴結構域和額外末端結構域顯示與間質性肺疾病相關的系統性硬化症的治療潛力江佳亮李珍珍中國醫藥大學生物醫學研究所
27	Limiting Lung Extracellular Adenosine Triphosphate Levels Alleviates Asthmatic Airway Inflammation 透過抑制肺部胞外三磷酸腺苷達成緩解氣喘發炎反應黃永安、郭敏玲長庚大學生物醫學研究所
28	TLR2 signaling able to restore the impaired expression of tight junction proteins by Th2-associated cytokines in keratinocytes TLR2訊號可恢復第二幫助型T細胞相關細胞激素所誘導的皮膚角質細胞緊密連結蛋白表現之缺失呂方媛^1#，莊惠雯^1#，陳惠珊¹，沈家瑞^1,3* 1長庚大學醫學生物技術暨檢驗學系、2明志科技大學化工系、3林口長庚醫院視網膜科
29	Microglia reduce herpes simplex virus 1 lethality of mice with decreased inflammation and increased neurotrophic factors in brains 微膠細胞降低單純疱疹病毒第一型在小鼠的致死性且在小鼠腦中減緩發炎與增加神經滋養因子蔡孟珊¹ 王莉萩² 陳舜華^1,3 1國立成功大學基礎醫學研究所 2義守大學醫學系 3國立成功大學微生物及免疫學研究所
30	Galectin-3 promotes non-canonical inflammasome activation through LPS glycans recognition 半乳醣凝集素-3透過細胞內脂多醣上的聚醣結合進而促進非典型的炎性體活化駱子翰陳宏霖翁宜君劉扶東中研院國際研究生分子醫學學程中央研究院生物醫學科學研究所美國加利福尼亞大學戴維斯分校醫學院皮膚科
31	ROS-mediated Src homology 2-containing protein tyrosine phosphatase 2 contributes to TGFβ-induced skin epithelial-mesenchymal transition 活性氧化物質媒介酪胺酸蛋白去磷酸酶促進乙型轉化因子誘導皮膚上皮細胞間質轉化游景鈞^1,2，林秋烽^1,2 臺北醫學大學1醫學科學研究所2微生物暨免疫學科
32	Metformin treatment may modulate allergic inflammation in a mouse model of asthma Metformin減輕小鼠肺部過敏性發炎之免疫調節機制翁子軒孫昭玲高雄醫學大學醫學研究所高雄醫學大學環境醫學研究中心
33	The regulatory effects of corticosteroids for collagen contraction on human buccal fibroblasts in vitro 皮質類固醇於口腔纖維母細胞體外試驗中對膠原蛋白收縮的調節功效林其懋江伯倫葉怡玲臺大雲林分院耳鼻喉部臺大醫院醫學研究部虎尾科技大學生物科技系
34	Low-Dose exposure to Di-(2-ethylhexyl) phthalate promotes allergic lung inflammation by modulating dendritic cell function through Peroxisome Proliferator-Activated Receptor gamma 長期低劑量暴露DEHP會透過PPARγ其機制調節樹突狀細胞功能而促進過敏性氣喘的肺部發炎反應曾馨漢吳欣庭黃嘯谷孫昭玲高雄醫學大學醫學研究所國家衛生研究院環境醫學研究所高雄醫學大學環境醫學研究中心
35	Role of Equilibrative Nucleoside Transporter 3 (ENT3) in Microglia and Its Possible Involvement in Neurodegenerative Conditions 平衡核苷轉運蛋白3（ENT3）在小膠質細胞中扮演的角色以及可能參與在神經退化性疾病中的作用呂瑩穗洪秉煜陳儀莊徐嘉琳* 國立陽明大學微生物及免疫學研究所中央研究院生物醫學科學研究所
36	Noscapine attenuated auto-immune disease by reducing the polarization of Th17 cells and the expression of HIF1α 鎮咳藥諾司卡賓透過下調缺氧誘導因子-1α表現並降低輔助型T細胞17分化減緩自體免疫疾病發病進展楊立瑄蔡忠穎葛依青林銜德楊皇煜林口長庚紀念醫院腎臟研究中心腎臟科
37	Cisd2 deficiency causes age-related T cell dysfunctions and impairs B cell responses 探討Cisd2調控老化相關T細胞功能缺失與降低B細胞反應之角色周奕如¹,林慶政²,劉晨風³,楊馥蓁²,劉文賢^3,陳念榮^2 蔡亭芬^1,4,5,6* 1國家衛生研究院分子與基因醫學研究所 2國立陽明大學微生物及免疫學研究所 3廈門大學生命科學學院 4國立陽明大學生命科學系暨基因體科學研究所 5國家衛生研究院生技與藥物研究所 6國立陽明大學高齡與健康研究中心
38	Senescence exacerbates the impact of Tid-1 deficiency on B cell development inhibition 老化加重休克蛋白40共伴侶蛋白Tid1缺乏時對B細胞發育的抑制現象 Stephanie Sayson^1,2 范家寧¹ 羅正汎³ 周秀慧¹ 1天主教輔仁大學生命科學系 2天主教輔仁大學應用科學與工程研究所 3陽明大學口腔生物研究所
39	Development of Influenza A Virus NS1 Mutant Strains with Higher Type I IFN Production as Vaccine Candidates 開發有更高第一型干擾素產生的A型流感病毒NS1突變株來作為疫苗馬聖凱¹，施孟岑²，張宏全¹，陳銘發¹，凌斌^1,2,* 1國立成功大學微生物及免疫學研究所 2醫學檢驗暨生物技術學系所
40	Imiquimold Microneedle Patch for the Treatment of Warts: a Proof-of-Concept Study 以Imiquimod微針貼片治療病毒疣的概念驗證研究邱足滿、徐秉鈞、莫陽凱、李俊洪、林政鞍、徐再靜、陳民樺*、花方信孝彰化基督教醫院皮膚科、中原大學生物醫學工程學系、中山醫學大學醫學研究所、中山醫學大學臨床實驗室、國立物質材料研究機構(日本)
41	Characterization of monoclonal antibodies against Staphylococcus aureus alpha-enolase 製備抗金黃色葡萄球菌α-異烯醇酶單株抗體王唯竹¹ 蔡聚瑄² 楊沂淵^2,3 呂思潔^1,4* 臺北醫學大學醫學科學研究所臺北醫學大學醫學檢驗暨生物技術學系臺北醫學大學抗體及融合瘤核心實驗室臺北醫學大學微生物與免疫學科
42	Differential effects of different human parvovirus B19V-VP1 unique region fragments on cardiac injuries in naïve mice 人類微小病毒B19殼體蛋白獨立區域不同片段對naïve小鼠心臟損傷的差異作用游家樂^1,2 洪國全³ 黃子芸¹ 張嘉玲² 徐再靜^1,* 曾博修^1,2,* 中山醫學大學醫學研究所1, 中山醫學大學醫學系生化科2, 奇美醫院麻醉科3
43	Investigation of CLEC5A-mediated induction of γδT17 in promoting host defense during Listeria monocytogenes infection 探討CLEC5A在李斯特菌感染後藉由調節γδT17分化以促進宿主防禦之角色陳家華,趙之偉,陳斯婷國立陽明大學臨床醫學研究所
44	Inflammation Core Facility Service: Investigation of the cells and cytokines underlying a traditional Chinese medicine in dextran sulfate sodium-induced colitis mouse model 發炎核心設施服務：研究一種中藥在潰瘍性結腸炎小鼠模型中的細胞和細胞因子楊雅婷^1,2, 許家豪^1,2, 洪聿賢^1,2, 王人雙^1,2, 盧傳棻^1,2, 林民昆³, 劉扶東¹, 陳煥源^1,2 1中央研究院生物醫學科學研究所 2中央研究院生物醫學科學研究所發炎核心設施 3中國醫藥大學中醫學院中國藥學暨中藥資源學系
45	Role of microRNA-17-92 in modulating rejection response in a mouse skin transplantation model 剔除微核糖核酸17-92減輕由濾泡性B輔助性T細胞引起之皮膚移植排斥張軒嘉郭彥志葛依青蔡忠穎楊皇煜林口長庚醫院腎臟醫學研究中心
46	NLRP12 regulates noncanonical inflammasome via IFN-type 1 signaling to limit GSDMD cleavage and Neutrophil extracellular traps. Babamale Olarewaju Abdulkareem(巴巴馬) 陳斯婷陽明大學臨床醫學研究所

海報論文目錄

1

Immunomodulatory activity of 2-methoxycinnamaldehyde

2

Agonistic anti-CD40 monoclonal antibody drives novel metabolic reprograming to trigger M1 macrophages activation

3

Adenosine 2B receptor promotes IL-10 production by B1a B cells and regulates germinal center-derived autoimmunity in MRL/lpr mice

4

New CD1d-restricted glycolipids inhibits iNKT-mediated inflammation in mice

5

To Study the Immunosuppressive Activity of Cyn-1324 in Ovalbumin-sensitized Asthmatic Mice

6

TREM-2-mediated Nitric Oxide Ameliorate UUO-induced Renal Pathologies through Nitration of RORγt

7

Investigation of the effect of Parkinson’s disease-associated leucine-rich repeat kinase 2 on immune response

8

Investigating the effects of Candida tropicalis on experimental colitis

9

Characterization of the mechanisms of anti-GM-CSF monoclonal antibodies isolated from cryptococcosis patients

10

TREM-1 Expressing Tumor associated macrophages (TAMs)Play a Role of Anti-cancer

11

Characteristics the properties of anti-PLA2R antibodies from Membranous nephropathy patients

12

GILT contributes to the development of autoimmune uveitis in a murine uveitis model induced by active immunizations

13

Anti-IFN-γ autoantibodies underlie disseminated Talaromyces marneffei infections

14

Investigation of the molecular mechanism and signal transduction of GPR97-mediated apoptosis delay of human neutrophils

15

Inhaled Exposure to Acrylamide Enhances Allergic Lung Inflammation in a Murine Model

16

Widespread methylome variations of gout

17

Schisandrin B exerts antiallergic effects in Th2-mediated allergic asthma via induction of Foxp3+ regulatory T cells by modulating the function of dendritic cells

18

Heparan Sulfate Is Important for Thymus Growth

19

Regulation of T-independent B cell response by conventional dendritic cells

20

Thymic macrophages are derived from embryonic precursors

21

The Presence of Apoptotic Thymocytes Regulates the Expression of Ferroportin (SLC40A1) in Thymic Resident Macrophages

22

Dectin-1-NLRP3 inflammasome signaling-dependent mucus secretion guards intestinal epithelium from fungal invasion

23

Identification and characterization of a novel cellular ligand of GPR97/ADGRG3 in human neutrophils

24

Rosmarinic Acid Attenuates Lipopolysaccharide-induced Acute Lung Injury in a Murine Model

25

Characterization of anti-interferon-γ autoantibodies from patients with mycobacterial disease in the monoclonal level

26

Targeting bromodomain and extra terminal domain showed therapeutic potential for systemic sclerosis associated with interstitial lung disease

27

Limiting Lung Extracellular Adenosine Triphosphate Levels Alleviates Asthmatic Airway Inflammation

28

TLR2 signaling able to restore the impaired expression of tight junction proteins by Th2-associated cytokines in keratinocytes

29

Microglia reduce herpes simplex virus 1 lethality of mice with decreased inflammation and increased neurotrophic factors in brains

30

Galectin-3 promotes non-canonical inflammasome activation through LPS glycans recognition

31

ROS-mediated Src homology 2-containing protein tyrosine phosphatase 2 contributes to TGFβ-induced skin epithelial-mesenchymal transition

32

Metformin treatment may modulate allergic inflammation in a mouse model of asthma

33

The regulatory effects of corticosteroids for collagen contraction on human buccal fibroblasts in vitro

34

Low-Dose exposure to Di-(2-ethylhexyl) phthalate promotes allergic lung inflammation by modulating dendritic cell function through Peroxisome Proliferator-Activated Receptor gamma

35

Role of Equilibrative Nucleoside Transporter 3 (ENT3) in Microglia and Its Possible Involvement in Neurodegenerative Conditions

36

Noscapine attenuated auto-immune disease by reducing the polarization of Th17 cells and the expression of HIF1α

37

Cisd2 deficiency causes age-related T cell dysfunctions and impairs B cell responses

38

Senescence exacerbates the impact of Tid-1 deficiency on B cell development inhibition

39

Development of Influenza A Virus NS1 Mutant Strains with Higher Type I IFN Production as Vaccine Candidates

TREM-1 Expressing Tumor associated macrophages (TAMs)
Play a Role of Anti-cancer